Can testosterone shots prevent diabetes in men?
University of Sydney researchers are seeking male participants for a novel trial assessing whether regular testosterone shots can prevent type 2 diabetes in men.
The $4.8 million Testosterone for the prevention of Diabetes Mellitus (T4DM) study – the first of its kind in the world – is looking at the potential benefits of treating men with early signs of the condition (pre-diabetes) with testosterone supplements in conjunction with a dedicated weight-loss program.
The researchers are seeking up to 1500 overweight male participants aged 50-74 for this ground-breaking study ranging across NSW, Victoria, South Australia and Western Australia.
Lead investigator, Associate Professor Ann Conway, said men who sign up for the study would have free access to the online weight-loss program run by Weight Watchers.
“An online program is ideal for men who prefer not to attend Weight Watchers meetings,” she said.
"By giving testosterone supplements to men in that critical pre-diabetes stage, and by putting them on a dedicated weight-loss program, we hope to see sustained reductions in weight and a reduced chance to develop type 2 diabetes.
“Older men who have developed a large belly and are at risk of diabetes now have an opportunity to do something about their weight, improve their lives, and provide us with all-important research results that could benefit many others in the future."
Dr Conway said in the first six months of study participation, 77 per cent of men lost weight.
“This study has provided the impetus to finally make the long term life style changes I know I should be implementing, while offering an opportunity to contribute to ongoing research in this area.”
To potential trial participants, Mr Pryke said: “Go for it – you have nothing to lose and an enormous amount to gain.
“Proving the role of testosterone in weight loss will be important and I believe publicity around the positive impacts on the lives of the men who actively participate will have a broader impact.”
Fellow trial participant, Dr Tony Partridge said he had learnt more about pre diabetes and making the relevant lifestyle changes as a result of participating in the trial.
“I have a healthy self-image and an active life-style so I was surprised to find I was at risk,” he said.
“Give it a go. You might help others to better health and perhaps also help yourself if risk factors are indicated.”
This study is funded by the National Health and Medical Research Council (NHMRC).
Trial contact and interviews: Associate Professor Ann Conway, 02 9767 7222, 0419 011 357 or firstname.lastname@example.org
Media contact: Rachel Gleeson 02 9351 4630, 0481 004 782, email@example.com